Plaque Psoriasis

What is Plaque Psoriasis? Plaque psoriasis, also known as psoriasis vulgaris, is a chronic, autoimmune skin disorder that causes thick, raised, red, scaly patches with sharply defined margins known as plaques on the skin. It is the most common form of psoriasis, accounting for 80-90% of cases. Although psoriasis presents most commonly between the ages of 15-35 years, anyone may be affected.

 

What causes Plaque Psoriasis?

 

The exact cause of plaque psoriasis is not fully understood, but it is thought to be a combination of several factors:

 

  • Genetics
  • Immune system dysfunction associated with activation of TH17  by IL-23.
  • Environmental triggers, such as stress, infection, and injury to the skin.

 

Sign and Symptoms of Plaque Psoriasis

 

  • Raised, red, scaly patches on the skin, often covered in silver-white scales
  • Itching, burning, or soreness around the patches
  • Dry, cracked skin that may bleed
  • Thickened, pitted or ridged nails
  • Joint pain or stiffness (in some cases)

Source: Yan, B., Chen, X., Ye, L., Chen, J., Zheng, M., & Man, X. (2021). Cutaneous and Systemic Psoriasis: Classifications and Classification for the Distinction.  , 8. https://doi.org/10.3389/fmed.2021.649408