Neuroinflammation

What is Neuroinflammation? Neuroinflammation refers to the immune response in the central nervous system (CNS) that involves the activation of glial cells, such as microglia and astrocytes, and the release of pro-inflammatory cytokines, chemokines, and reactive oxygen species. While there are benefits to transient, low levels of neuroinflammation in the brain, such as immune surveillance, enhancing neuroplasticity, and aiding in tissue repair, chronic or high levels of neuroinflammation can have detrimental effects on the normal physiology of the nervous system. It plays a critical role in the pathophysiology of several neurological disorders, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and stroke.