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Objective Endpoints

What are objective endpoints? Objective endpoints are measurable outcomes of a clinical trial and do not consider the subject’s feelings. Objective endpoints can be clinical endpoints, such as survival and risk, or non-clinical endpoints, such as blood tests. Objective endpoints are less vulnerable to bias.

What are the disadvantages of objective endpoints? 

Objective endpoints, especially non-clinical endpoints, require testing, which may be time- sensitive, expensive, and have the risk of laboratory errors.

Source: Evans S. R. (2010). Fundamentals of clinical trial design. Journal of experimental stroke & translational medicine, 3(1), 19–27. https://doi.org/10.6030/1939-067x-3.1.19