Other terms
- Fundus Diseases
- Ganglion cyst
- Gastric Cancer
- Gastric Ulcer
- Gastroenteritis
- Gastroenterology
- Irritable Bowel Syndrome (IBS)
- Gene Therapy
- Genitourinary System
- Genomics
- Geriatric Neurology
- Glaucoma
Functional Dyspepsia
What is Functional Dyspepsia? Functional dyspepsia is a common, chronic disorder, but benign of the upper gastrointestinal tract affecting 20% of the general population worldwide. It has a higher prevalence in women, older adults, and those with a history of anxiety or depression.
What Causes Functional Dyspepsia?
The exact cause of functional dyspepsia is still unknown, but it is believed to be multifactorial, involving the interplay of genetic, environmental, and psychological factors.
Alterations in gut motility, hypersensitivity to gastric distension, and impaired gastric accommodation are also thought to play a role in the pathomechanism, but no structural or biochemical abnormalities are associated with the disease.
Risk factors include:
- Enteric infections
- Recent antibiotic use
- Frequent use of NSAIDs
- Overweight
- Smoking
- Psychosocial dysfunction
Signs and Symptoms of Functional Dyspepsia
- Recurrent epigastric pain or discomfort
- Bloating
- Early satiety
- Postprandial fullness
- Nausea/vomiting
- Belching
- Heartburn
Source: Mahadeva, S., & Goh, K. (2006). Epidemiology of functional dyspepsia: A global perspective. World Journal of Gastroenterology, 12(17), 2661. https://doi.org/10.3748/wjg.v12.i17.2661
