Pulmonary Hypertension

Pulmonary hypertension (PH) comprises a group of diseases that cause elevated blood pressure in the pulmonary arteries. Pulmonary hypertension is diagnosed when the mean arterial pressure (mPAPA) is measured by right-sided heart catheterization and is found to be equal to or greater than 20 mmHg at rest.

It is caused by a variety of underlying conditions and is usually a manifestation of advanced disease. Approximately 1% of the global population and 50% of those with heart failure experience pulmonary hypertension.

 

Types of Pulmonary Hypertension

 

Pulmonary hypertension has been classified by WHO into five categories based on etiology. 

 

  1. Pulmonary arterial hypertension (PAH)
  2. Pulmonary hypertension due to left-sided heart disease
  3. Pulmonary hypertension due to chronic lung disease and/or hypoxia
  4. Chronic thromboembolic pulmonary hypertension (CTEPH)
  5. Pulmonary hypertension due to unknown cause

Source: Mandras, S., Mehta, H., & Vaidya, A. (2020). Pulmonary Hypertension: A Brief Guide for Clinicians. Mayo Clinic Proceedings, 95(9), 1978–1988. https://doi.org/10.1016/j.mayocp.2020.04.039