Randomization is an allocation strategy that assigns participants to treatment or control groups using an element of chance.

The benefit of randomization is that it reduces the risk of accidental biases such as selection bias. It also promotes similarity of study groups and increases the validity of the study.

The process of randomization can be adapted to suit the needs of the clinical trial and further eliminate bias by employing restrictive or stratified randomization methodologies.

Source: Lim, C. Y., & In, J. (2019). Randomization in clinical studies. Korean journal of anesthesiology, 72(3), 221–232. https://doi.org/10.4097/kja.19049