Phase III

Phase III is described as the phase for comparative and efficacy trials. The primary focus of Phase III studies is to confirm benefit by investigating the efficacy in large groups of human subjects (100s-1000s). This is accomplished by comparing the intervention to other standard or experimental interventions.

Other goals of Phase III trials include:

  • Expanding knowledge of safety of the intervention.
  • Evaluating overall risk versus benefit.
  • Providing adequate basis for labeling.

Source: Types and Phases of Clinical Trials | What Are Clinical Trial Phases? (n.d.). American Cancer Society. Retrieved January 8, 2022, from