Molecular Profiling

What is Molecular Profiling? Molecular profiling refers to the process of analyzing the molecular characteristics of a biological sample, such as DNA, RNA, or proteins. This technique is used for various purposes, including diagnosis, treatment selection, and disease monitoring.

Examples of molecular profiling techniques include:

 

  • Immunohistochemistry
  • Next generation sequencing
  • Qualitative polymerase chain reaction

 

Applications of Molecular Profiling

 

  • Personalized medicine through the tailoring of treatments to the unique genetic makeup of an individual patient, resulting in better outcomes and fewer adverse effects.
  • Early diagnosis through the identification of genetic mutations and biomarkers associated with various diseases.
  • Targeted therapies through understanding the molecular drivers of disease.
  • Monitoring treatment response.

Source: Lim, J. S., Brown, J. A., & De Bono, J. S. (2018). Can Early Clinical Trials Help Deliver More Precise Cancer Care? Novel Designs of Early Phase Trials for Cancer Therapeutics. https://doi.org/10.1016/b978-0-12-812512-0.00009-9