Trovafloxacin

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Scientific Name: Trovafloxacin
Brand Name: Trovan
Company Owner: Pfizer chemicals div pfizer inc, Pfizer central research
Mechanism Of Action Trovafloxacin is a fluoronaphthyridone related to the fluoroquinolones with in vitro activity against a wide range of gram-negative and gram-positive aerobic and anaerobic microorganisms. The bactericidal action of trovafloxacin results from inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription, and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.
Description of the Drug: Trovafloxacin is an antibiotic used to treat gonorrhea and chlamydia.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00685