Abemaciclib

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Molecule Structure

Scientific Name

Abemaciclib

Description of the Drug

Abemaciclib is a medication used to treat HR+ HER2- advanced or metastatic breast cancer.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB12001

Brand Name(s)

Verzenio, Verzenios

Company Owner(s)

Eli Lilly And Co

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Cyclin-dependent kinase 4 SINGLE PROTEIN INHIBITOR CHEMBL331
Cyclin-dependent kinase 6 SINGLE PROTEIN INHIBITOR CHEMBL2508

Unichem Links

SureChEMBL SCHEMBL2487229
PharmGKB PA166153471
Human Metabolome Database HMDB0247749
DrugBank DB12001
PubChem: Thomson Pharma 96075034
PubChem 46220502
LINCS LSM-46168 LSM-46205
Nikkaji J3.307.988E
PDBe 6ZV
BindingDB 50110183
EPA CompTox Dashboard DTXSID20673119
DrugCentral 5259
ChemicalBook CB72624906
Guide to Pharmacology 7382
rxnorm ABEMACICLIB VERZENIO
ZINC ZINC000072318121