Tropisetron

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Scientific Name: Tropisetron
Brand Name: Not Available
Company Owner: Not Available
Mechanism Of Action Tropisetron competitively binds to and blocks the action of serotonin at 5HT3 receptors peripherally on vagus nerve terminals located in the gastrointestinal (GI) tract as well as centrally in the chemoreceptor trigger zone (CTZ) of the area postrema of the central nervous system (CNS) . This results in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Description of the Drug: Tropisetron is a 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB11699