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Scientific Name: Tranylcypromine
Brand Name: Parnate
Company Owner: Glaxosmithkline, Par pharmaceutical inc
Mechanism Of Action Tranylcypromine irreversibly and nonselectively inhibits monoamine oxidase (MAO) . Within neurons, MAO appears to regulate the levels of monoamines released upon synaptic firing. Since depression is associated with low levels of monoamines, the inhibition of MAO serves to ease depressive symptoms, as this results in an increase in the concentrations of these amines within the CNS.
Description of the Drug: Tranylcypromine is a monoamine oxidase inhibitor used to treat major depressive disorder.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from