Molecule Structure

Scientific Name

Thiotepa

Description of the Drug

Thiotepa is an alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB04572

Brand Name(s)

Tepadina, Thioplex, Thiotepa

Company Owner(s)

Sti Pharma Llc, Immunex Corp, Teva Parenteral Medicines Inc, West-Ward Pharmaceuticals International Ltd, Fresenius Kabi Usa Llc, Dr Reddys Laboratories Ltd, Adienne Sa, Gland Pharma Ltd, Msn Laboratories Private Ltd, Jiangsu Hengrui Medicine Co Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
DNA NUCLEIC-ACID INHIBITOR CHEMBL2311221

Unichem Links

SureChEMBL SCHEMBL4760
Human Metabolome Database HMDB0015576
WDI THIOTEPA
DrugBank DB04572
PubChem: Thomson Pharma 15322228
PubChem 5453
Mcule MCULE-5478761622
LINCS LSM-2194
Nikkaji J2.307H
BindingDB 50418086
EPA CompTox Dashboard DTXSID0021339
DrugCentral 2638
ChemicalBook CB0458870
Guide to Pharmacology 7622
GSRS 97ee5fb3-6cc3-4475-8092-792b7d8aaa99
rxnorm TEPADINA THIOTEPA
KEGG Ligand C07641
ChEBI 9570
ZINC ZINC000001530867