Thiotepa
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Scientific Name
Thiotepa
Description of the Drug
Thiotepa is an alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB04572
http://www.drugbank.ca/drugs/DB04572
Brand Name(s)
Tepadina, Thioplex, Thiotepa
Company Owner(s)
Sti Pharma Llc, Immunex Corp, Teva Parenteral Medicines Inc, West-Ward Pharmaceuticals International Ltd, Fresenius Kabi Usa Llc, Dr Reddys Laboratories Ltd, Adienne Sa, Gland Pharma Ltd, Msn Laboratories Private Ltd, Jiangsu Hengrui Medicine Co Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| DNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311221 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL4760 | |
| Human Metabolome Database | HMDB0015576 | |
| WDI | THIOTEPA | |
| DrugBank | DB04572 | |
| PubChem: Thomson Pharma | 15322228 | |
| PubChem | 5453 | |
| Mcule | MCULE-5478761622 | |
| LINCS | LSM-2194 | |
| Nikkaji | J2.307H | |
| BindingDB | 50418086 | |
| EPA CompTox Dashboard | DTXSID0021339 | |
| DrugCentral | 2638 | |
| ChemicalBook | CB0458870 | |
| Guide to Pharmacology | 7622 | |
| GSRS | 97ee5fb3-6cc3-4475-8092-792b7d8aaa99 | |
| rxnorm | TEPADINA | THIOTEPA |
| KEGG Ligand | C07641 | |
| ChEBI | 9570 | |
| ZINC | ZINC000001530867 |
