Pemetrexed
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Scientific Name
Pemetrexed
Description of the Drug
Pemetrexed is a folate analog used to treat mesothelioma and non-small cell lung cancer.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00642
http://www.drugbank.ca/drugs/DB00642
Brand Name(s)
Alimta, Pemfexy
Company Owner(s)
Apotex Inc, Fresenius Kabi Usa Llc, Sandoz Inc, Hospira Inc, Jiangsu Hansoh Pharmaceutical Group Co Ltd, Eli Lilly And Co, Accord Healthcare Inc, Eugia Pharma Specialities Ltd, Dr Reddys Laboratories Ltd, Nang Kuang Pharmaceutical Co Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Dihydrofolate reductase | SINGLE PROTEIN | INHIBITOR | CHEMBL202 |
| Thymidylate synthase | SINGLE PROTEIN | INHIBITOR | CHEMBL2555 |
| GAR transformylase | SINGLE PROTEIN | INHIBITOR | CHEMBL3972 |
| Thymidylate synthase | SINGLE PROTEIN | INHIBITOR | CHEMBL1952 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL7968 | ||||
| DrugBank | DB00642 | ||||
| PubChem: Thomson Pharma | 15378661 | 14758615 | |||
| PubChem | 135410875 | ||||
| LINCS | LSM-6353 | ||||
| Nikkaji | J696.080D | ||||
| PDBe | LYA | ||||
| BindingDB | 50027656 | 18796 | |||
| EPA CompTox Dashboard | DTXSID2048329 | ||||
| DrugCentral | 2073 | ||||
| Brenda | 1155 | 209750 | 125093 | 209752 | 56903 |
| ChemicalBook | CB4170583 | ||||
| rxnorm | PEMETREXED DISODIUM HEPTAHYDRATE | PEMETREXED DISODIUM | PEMETREXED | ALIMTA | |
| ChEBI | 63616 | ||||
| ZINC | ZINC000001540998 |
