Lamivudine

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Molecule Structure

Scientific Name

Lamivudine

Description of the Drug

Lamivudine is a reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00709

Brand Name(s)

Epivir, Epivir-hbv, Lamivudine, Zeffix

Company Owner(s)

Lannett Co Inc, Celltrion Inc, Apotex Inc, Lupin Ltd, Merck Sharp And Dohme Corp, Zydus Pharmaceuticals Usa Inc, Annora Pharma Private Ltd, Anda Repository Llc, Mylan Pharmaceuticals Inc, Hetero Labs Ltd Unit V

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
DNA polymerase/reverse transcriptase SINGLE PROTEIN INHIBITOR CHEMBL2362994
DNA NUCLEIC-ACID INHIBITOR CHEMBL2363046
DNA NUCLEIC-ACID INHIBITOR CHEMBL2363047
Human immunodeficiency virus type 1 reverse transcriptase SINGLE PROTEIN INHIBITOR CHEMBL247
DNA NUCLEIC-ACID INHIBITOR CHEMBL2363048

Unichem Links

SureChEMBL SCHEMBL109675
PharmGKB PA450163
Human Metabolome Database HMDB0014847
WDI GR109714X
DrugBank DB00709
PubChem: Thomson Pharma 14798125 15121620
PubChem 60825
Mcule MCULE-8483986532 MCULE-2096184994
LINCS LSM-5215
Nikkaji J457.051K
PDBe 3TC
BindingDB 50366817
DrugCentral 1539
Brenda 229604 4247 228663 229605 6246
ChemicalBook CB1290608
GSRS 75aef525-0768-4d1f-9548-6589da8cfdcb
rxnorm LAMIVUDINE EPIVIR
PubChem: Drugs of the Future 12014700
KEGG Ligand C07065
ChEBI 63577
NIH Clinical Collection SAM002589994 SAM001246582
ZINC ZINC000000012346