Indomethacin

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Molecule Structure

Scientific Name

Indomethacin

Description of the Drug

Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-02-07 from
http://www.drugbank.ca/drugs/DB00328

Brand Name(s)

Artracin, Artracin sr, Berlind 75 ret, Flexin-25 continus, Flexin-50 continus, Flexin-75 continus, Imbrilon, Indocid-r, Indocid ret, Indocin, Indocin sr, Indoderm, Indoflex, Indolar, Indolar sr, Indo-lemmon, Indomax-25, Indomax-75 sr, Indomethacin, Indomod, Indo-paed, Indoptol, Indotard mr 75, Ledmecin, Maximet sr, Mobilan, Pardelprin mr, Rheumacin la, Rimacid, Slo-indo, Tivorbex

Company Owner(s)

Watson Laboratories Inc, Genus Lifesciences Inc, Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Amneal Pharmaceuticals, Chartwell Molecules Llc, Fresenius Kabi Usa Llc, Zydus Pharmaceuticals Usa Inc, Heritage Pharmaceuticals Inc Dba Avet Pharmaceuticals Inc, Ani Pharmaceuticals Inc, Mylan Pharmaceuticals Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Cyclooxygenase PROTEIN FAMILY INHIBITOR CHEMBL2094253

Unichem Links

Atlas indomethacin indometacin
SureChEMBL SCHEMBL9300
PharmGKB PA449982
Human Metabolome Database HMDB0014473
WDI CHINO-137 INDOMETAC
DrugBank DB00328
PubChem: Thomson Pharma 14754602
PubChem 3715
Mcule MCULE-5636486088
NMRShiftDB 20208999
LINCS LSM-3275
Nikkaji J1.368D
PDBe IMN
BindingDB 17638
EPA CompTox Dashboard DTXSID9020740
DrugCentral 1440
Metabolights MTBLC49662
Brenda 121822 125887 127068 98002
ChemicalBook CB1750267
Guide to Pharmacology 1909
GSRS 36bb067c-6dfc-4a3a-b81f-19f15a5ebb5a
rxnorm TIVORBEX INDOMETHACIN SODIUM INDOCIN INDOMETHACIN
KEGG Ligand C01926
ChEBI 49662
ZINC ZINC000000601283