Dichlorphenamide

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Molecule Structure

Scientific Name

Dichlorphenamide

Description of the Drug

Diclofenamide is a carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01144

Brand Name(s)

Daranide, Keveyis, Oratrol

Company Owner(s)

Xeris Pharmaceuticals Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Carbonic anhydrase IV SINGLE PROTEIN INHIBITOR CHEMBL3729
Carbonic anhydrase II SINGLE PROTEIN INHIBITOR CHEMBL205
Carbonic anhydrase I SINGLE PROTEIN INHIBITOR CHEMBL261
Carbonic anhydrase XII SINGLE PROTEIN INHIBITOR CHEMBL3242

Unichem Links

SureChEMBL SCHEMBL112376
PharmGKB PA164745512
Human Metabolome Database HMDB0015275
DrugBank DB01144
PubChem: Thomson Pharma 14898599
PubChem 3038
Mcule MCULE-4570158631
LINCS LSM-3602
Nikkaji J8.589H
PDBe I7A
BindingDB 10883
EPA CompTox Dashboard DTXSID1022922
DrugCentral 864
Brenda 19502 2179 2228 227816
ChemicalBook CB8129776
Guide to Pharmacology 6807
rxnorm KEVEYIS DICHLORPHENAMIDE
KEGG Ligand C07459
ChEBI 101085
ZINC ZINC000000896918