Dextrothyroxine
Back to search| Scientific Name: | Dextrothyroxine |
| Brand Name: | Not Available |
| Company Owner: | Abbott laboratories pharmaceutical products div |
| Mechanism Of Action | Dextrothyroxine is a antihyperlipidemic. The mechanism of action is not completely understood, but dextrothyroxine apparently acts in the liver to stimulate formation of low-density lipoprotein (LDL) and, to a much greater extent, to increase catabolism of LDL. This leads to increased excretion of cholesterol and bile acids via the biliary route into the feces, with a resulting reduction in serum cholesterol and LDL. Dextrothyroxine has no significant effect on high-density lipoproteins (HDL) . Inherently, it will also bind to thyroid receptors and as it is a prohormone, it will bind as a substrate to iodide peroxidase. |
| Description of the Drug: | Dextrothyroxine is a thyroid hormone used to treat hyperlipidemia. |
| Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00509
