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Scientific Name: Dexmedetomidine
Brand Name: Dexdor, Igalmi, Precedex
Company Owner: Hospira inc
Mechanism Of Action Dexmedetomidine is a specific and selective alpha-2 adrenoceptor agonist. By binding to the presynaptic alpha-2 adrenoceptors, it inhibits the release if norepinephrine, therefore, terminate the propagation of pain signals. Activation of the postsynaptic alpha-2 adrenoceptors inhibits the sympathetic activity decreases blood pressure and heart rate.
Description of the Drug: Dexmedetomidine is an alpha-2 agonist used for sedation during various procedures.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from