Desmopressin

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Scientific Name: Desmopressin
Brand Name: Ddavp, Nocdurna, Octostim
Company Owner: Sanofi aventis us llc, Bedford laboratories div ben venue laboratories inc, Hospira inc, Teva parenteral medicines inc, Ferring pharmaceuticals inc, Bausch and lomb pharmaceuticals inc, Apotex inc richmond hill, Csl behring llc, Apotex inc etobicoke site, Teva pharmaceuticals usa, Watson laboratories inc
Mechanism Of Action Upon binding of desmopressin to V2 receptors in the basolateral membrane of the cells of the distal tubule and collecting ducts of the nephron, adenylyl cyclase is stimulated. The resulting intracellular cascades in the collecting duct lead to increased rate of insertion of water channels, called aquaporins, into the lumenal membrane and enhanced the permeability of the membrane to water
Description of the Drug: Desmopressin is a synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00035