Carmustine

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Scientific Name: Carmustine
Brand Name: Bicnu, Gliadel
Company Owner: Eisai inc, Bristol laboratories inc div bristol myers co
Mechanism Of Action Carmustine causes cross-links in DNA and RNA, leading to the inhibition of DNA synthesis, RNA production and RNA translation (protein synthesis) . Carmustine also binds to and modifies (carbamoylates) glutathione reductase. This leads to cell death.
Description of the Drug: Carmustine is an alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00262