Carmustine
Back to searchScientific Name: | Carmustine |
Brand Name: | Bicnu, Gliadel |
Company Owner: | Eisai inc, Bristol laboratories inc div bristol myers co |
Mechanism Of Action | Carmustine causes cross-links in DNA and RNA, leading to the inhibition of DNA synthesis, RNA production and RNA translation (protein synthesis) . Carmustine also binds to and modifies (carbamoylates) glutathione reductase. This leads to cell death. |
Description of the Drug: | Carmustine is an alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others. |
Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00262