Belumosudil
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Scientific Name
Belumosudil
Description of the Drug
Belumosudil is an oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD).
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB16703
http://www.drugbank.ca/drugs/DB16703
Brand Name(s)
Not Available
Company Owner(s)
Kadmon Pharmaceuticals Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Rho-associated protein kinase 2 | SINGLE PROTEIN | INHIBITOR | CHEMBL2973 |
| Rho-associated protein kinase | PROTEIN FAMILY | INHIBITOR | CHEMBL2111459 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL878202 |
| Human Metabolome Database | HMDB0247641 |
| DrugBank | DB16703 |
| PubChem: Thomson Pharma | 17391529 |
| PubChem | 11950170 |
| LINCS | LSM-45630 |
| Nikkaji | J3.488.068I |
| PDBe | ICQ |
| BindingDB | 322155 |
| EPA CompTox Dashboard | DTXSID80238425 |
| ChemicalBook | CB82624291 |
| Guide to Pharmacology | 9558 |
| ZINC | ZINC000063298464 |
