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Central Retinal Vein Occlusion (CRVO)
What is Central Retinal Vein Occlusion (CRVO)? Central retinal vein occlusion (CRVO) is a subtype of retinal vein occlusion that occurs when a thrombus forms in the central retinal vein at the level of the lamina cribrosa of the optic news and involves subsequent damage to the entire retina. CRVO occurs less frequently than branch retinal vein occlusion (BRVO), affecting approximately 0.5% of adults in the United States.
Risk Factors of Central Retinal Vein Occlusion
Risk factors of CRVO include:
- Increased age
- Hypertension
- Hyperlipidemia
- Atherosclerosis
- Glaucoma
- Diabetes Mellitus
Signs and Symptoms of Central Retinal Vein Occlusion
Patients with CRVO often have an acute onset of pain in the affected eye with involvement of the entire retina.
Clinical signs visible on fundoscopy may include:
- Cotton wool spots
- Large retinal hemorrhages
- Marked venous tortuosity
- Macular edema
- Tractional retinal detachment
- Retinal neovascularization
Source: Scott, I. U., Campochiaro, P. A., Newman, N. J., & Biousse, V. (2020). Retinal vascular occlusions. The Lancet, 396(10266), 1927–1940. https://doi.org/10.1016/s0140-6736(20)31559-2
