Autoimmune Digestive Disorders

What Are Autoimmune Digestive Disorders? Autoimmune digestive disorders are a group of conditions in which the immune system inappropriately attacks the digestive system, leading to inflammation, damage, and dysfunction of the gastrointestinal tract.

Like most autoimmune diseases, the overall incidence of autoimmune digestive disorders is rising. While the causes of these diseases are multifactorial, genetics, such as associations with specific HLA phenotypes and Immunoglobulin G4- related conditions (IgG4-RD), play a significant role in their development.


What Are The Types of Autoimmune Digestive Disorders?

  • Celiac Disease
  • Inflammatory bowel diseases
  • Autoimmune hepatitis
  • Primary sclerosing cholangitis
  • Primary biliary cholangitis
  • Autoimmune pancreatitis
  • IgG4-related sclerosing cholangitis
  • IgG4-related hepatopathy

Source: Kunovský, L., Dite, P., Jabandžiev, P., Kala, Z., Vaculová, J., Andrašina, T., Hrunka, M., Bojková, M., & Trna, J. (2021). Autoimmune Diseases of Digestive Organs—A Multidisciplinary Challenge: A Focus on Hepatopancreatobiliary Manifestation. Journal of Clinical Medicine, 10(24), 5796.