Zoledronic acid

Back to search
Scientific Name: Zoledronic acid
Brand Name: Aclasta, Reclast, Zometa
Company Owner: Novartis pharmaceuticals corp
Mechanism Of Action Bisphosphonates are taken into the bone where they bind to hydroxyapatite. Bone resorption by osteoclasts causes local acidification, releasing the bisphosphonate, which is taken into the osteoclast by fluid-phase endocytosis.
Description of the Drug: Zoledronic acid is a bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00399