Vincristine
Back to searchScientific Name: | Vincristine |
Brand Name: | Marqibo, Vincasar |
Company Owner: | Eli lilly and co, Teva parenteral medicines inc, Bristol myers squibb, Abic ltd, Abraxis pharmaceutical products, App pharmaceuticals llc, Hospira inc |
Mechanism Of Action | The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkaloids, Vincristine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca |
Description of the Drug: | Vincristine is a vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin’s disease, acute erythraemia, and acute panmyelosis. |
Protein Data Bank: |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00541