Vernakalant
Back to searchScientific Name: | Vernakalant |
Brand Name: | Brinavess |
Company Owner: | Not Available |
Mechanism Of Action | Vernakalant blocks atrial voltage-gated sodium channels in a dose and frequency-dependent manner and inhibits late sodium current (INa) which confers its effect on intra-atrial conduction. This current blockade enhance and onset of drug action accelerates in higher heart rate as the affinity of vernakalant for INa also increases. Its binding offset is quick once the heart rate slows |
Description of the Drug: | Vernakalant is an antiarrhythmic medication used to treat patients with atrial fibrillation. |
Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB06217