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Scientific Name: Vernakalant
Brand Name: Brinavess
Company Owner: Not Available
Mechanism Of Action Vernakalant blocks atrial voltage-gated sodium channels in a dose and frequency-dependent manner and inhibits late sodium current (INa) which confers its effect on intra-atrial conduction. This current blockade enhance and onset of drug action accelerates in higher heart rate as the affinity of vernakalant for INa also increases. Its binding offset is quick once the heart rate slows
Description of the Drug: Vernakalant is an antiarrhythmic medication used to treat patients with atrial fibrillation.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from