Vemurafenib

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Molecule Structure

Scientific Name

Vemurafenib

Description of the Drug

Vemurafenib is a kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB08881

Brand Name(s)

Zelboraf

Company Owner(s)

Hoffmann La Roche Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Serine/threonine-protein kinase B-raf SINGLE PROTEIN INHIBITOR CHEMBL5145

Unichem Links

SureChEMBL SCHEMBL298931
PharmGKB PA165946873
Human Metabolome Database HMDB0259779
DrugBank DB08881
PubChem: Thomson Pharma 99207986
PubChem 42611257
Mcule MCULE-7244406627
LINCS LSM-1068
Nikkaji J2.870.988I
PDBe 032
BindingDB 50396483
EPA CompTox Dashboard DTXSID50238710
DrugCentral 4185
ChemicalBook CB22515128 CB02550000
Guide to Pharmacology 5893
rxnorm VEMURAFENIB ZELBORAF
PubChem: Drugs of the Future 123055406
ChEBI 63637
ZINC ZINC000052509366