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Scientific Name: Valdecoxib
Brand Name: Bextra
Company Owner: Gd searle llc
Mechanism Of Action Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane. Valdecoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, important for the mediation of inflammation and pain. Unlike non-selective NSAIDs, valdecoxib does not inhibit platelet aggregation.
Description of the Drug: Valdecoxib is a COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from