Valdecoxib
Back to search| Scientific Name: | Valdecoxib |
| Brand Name: | Bextra |
| Company Owner: | Gd searle llc |
| Mechanism Of Action | Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane. Valdecoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, important for the mediation of inflammation and pain. Unlike non-selective NSAIDs, valdecoxib does not inhibit platelet aggregation. |
| Description of the Drug: | Valdecoxib is a COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. |
| Protein Data Bank: |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00580
