Upadacitinib

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Scientific Name: Upadacitinib
Brand Name: Rinvoq
Company Owner: Not Available
Mechanism Of Action Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that involves the interplay of several mediators, including the immune cells (mainly T- and B-lymphocytes) and pro-inflammatory cytokines, such as the tumour necrosis factor (TNF) , transforming growth factor (TGF) , and interleukin 6 (IL-6) .
Description of the Drug: Upadacitinib is an oral Janus kinase (JAK) 1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, and severe atopic dermatitis, including in patients who did not respond well to other therapies.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB15091