Scientific Name: |
Trimethoprim |
Brand Name: |
Bactrim, Polytrim, Primsol, Septra, Sulfatrim |
Company Owner: |
Monarch pharmaceuticals inc, Mutual pharmaceutical co inc, Teva pharmaceuticals usa inc, Watson laboratories inc, Hoffmann la roche inc, Fsc laboratories inc |
Mechanism Of Action |
Trimethoprim is a reversible inhibitor of dihydrofolate reductase, one of the principal enzymes catalyzing the formation of tetrahydrofolic acid (THF) from dihydrofolic acid (DHF) . |
Description of the Drug: |
Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. |
Protein Data Bank: |
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