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Scientific Name: Trimethoprim
Brand Name: Bactrim, Polytrim, Primsol, Septra, Sulfatrim
Company Owner: Monarch pharmaceuticals inc, Mutual pharmaceutical co inc, Teva pharmaceuticals usa inc, Watson laboratories inc, Hoffmann la roche inc, Fsc laboratories inc
Mechanism Of Action Trimethoprim is a reversible inhibitor of dihydrofolate reductase, one of the principal enzymes catalyzing the formation of tetrahydrofolic acid (THF) from dihydrofolic acid (DHF) .
Description of the Drug: Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from