Trimethoprim
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Scientific Name
Trimethoprim
Description of the Drug
Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00440
http://www.drugbank.ca/drugs/DB00440
Brand Name(s)
Ipral, Ledatrim, Monotrim, Proloprim, Proloprin, Syraprim, Tiempe, Trimethoprim, Trimogal, Trimopan, Trimpex, Trimpex 200, Triprimix 200
Company Owner(s)
Sun Pharmaceutical Industries Inc, Watson Laboratories Inc, Bausch And Lomb Pharmaceuticals Inc, Novitium Pharma Llc, Able Laboratories Inc, Prasco Llc Dba Prasco Laboratories, Bedford Laboratories Div Ben Venue Laboratories Inc, Akorn Operating Co Llc, Vista Pharmaceuticals Inc, Teva Pharmaceuticals Usa Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Bacterial dihydrofolate reductase | SINGLE PROTEIN | INHIBITOR | CHEMBL2364669 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL24506 | ||||
| PharmGKB | PA451788 | ||||
| Human Metabolome Database | HMDB0014583 | ||||
| DrugBank | DB00440 | ||||
| PubChem: Thomson Pharma | 14824824 | ||||
| PubChem | 5578 | ||||
| Mcule | MCULE-6670904388 | ||||
| LINCS | LSM-5246 | ||||
| Nikkaji | J9.454D | ||||
| PDBe | TOP | ||||
| BindingDB | 18069 | ||||
| EPA CompTox Dashboard | DTXSID3023712 | ||||
| DrugCentral | 2755 | ||||
| Brenda | 55818 | 95248 | 503 | 252944 | 155221 |
| ChemicalBook | CB2745185 | ||||
| Guide to Pharmacology | 10931 | ||||
| rxnorm | TRIMETHOPRIM SULFATE | PRIMSOL | TRIMETHOPRIM HYDROCHLORIDE | TRIMETHOPRIM | |
| KEGG Ligand | C01965 | ||||
| ChEBI | 45924 | ||||
| ZINC | ZINC000006627681 |
