Trifluridine

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Molecule Structure

Scientific Name

Trifluridine

Description of the Drug

Trifluridine is a nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00432

Brand Name(s)

T.f.t., Trifluridine, Triherpine, Viroptic

Company Owner(s)

Sandoz Inc, Akorn Operating Co Llc, Monarch Pharmaceuticals Llc, Taiho Oncology Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
DNA NUCLEIC-ACID INHIBITOR CHEMBL2366042

Unichem Links

SureChEMBL SCHEMBL3479
PharmGKB PA451775
Human Metabolome Database HMDB0014576
DrugBank DB00432
PubChem: Thomson Pharma 14849367 14751529
PubChem 6256
LINCS LSM-5217
Nikkaji J2.814B
BindingDB 50132298
EPA CompTox Dashboard DTXSID4046602
DrugCentral 2743
Brenda 209608 252867 42444 252862 91973 210497
Guide to Pharmacology 8697
rxnorm VIROPTIC TRIFLURIDINE
PubChem: Drugs of the Future 12014784
ChEBI 75179
ZINC ZINC000003842753