Trifluoperazine

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Molecule Structure

Scientific Name

Trifluoperazine

Description of the Drug

Trifluoperazine is a phenothiazine used to treat depression, anxiety, and agitation.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00831

Brand Name(s)

Amylozine, Stelazine, Stelazine fte

Company Owner(s)

Fosun Pharma Usa Inc, Athem Holdings Llc, Glaxosmithkline, Sandoz Inc, Watson Laboratories Inc, Ivax Pharmaceuticals Inc, Wockhardt Eu Operations (Swiss) Ag, Mylan Pharmaceuticals Inc, Duramed Pharmaceuticals Inc Sub Barr Laboratories Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
D2-like dopamine receptor PROTEIN FAMILY ANTAGONIST CHEMBL2331075
Serotonin 2c (5-HT2c) receptor SINGLE PROTEIN ANTAGONIST CHEMBL225
Serotonin 2a (5-HT2a) receptor SINGLE PROTEIN ANTAGONIST CHEMBL224

Unichem Links

Atlas trifluoperazine
SureChEMBL SCHEMBL24866
PharmGKB PA451771
Human Metabolome Database HMDB0014969
DrugBank DB00831
PubChem: Thomson Pharma 14904043
PubChem 5566
Mcule MCULE-3726407978
NMRShiftDB 70021280
LINCS LSM-4010
Nikkaji J5.293K
PDBe TFP
BindingDB 79181
EPA CompTox Dashboard DTXSID1046928
DrugCentral 2740
Brenda 977 16220 129678 230160 6813 16001 230161
ChemicalBook CB9444115
Guide to Pharmacology 214
rxnorm TRIFLUOPERAZINE TRIFLUOPERAZINE HYDROCHLORIDE
KEGG Ligand C07168
ChEBI 45951
ZINC ZINC000019418959