Molecule Structure

Scientific Name

Tretinoin

Description of the Drug

Tretinoin is a vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00755

Brand Name(s)

Acticin, Altreno, Atralin, Avita, Renova, Retin-a, Retin-a micro, Retin-a-micro, Tretinoin, Tretin-X, Vesanoid

Company Owner(s)

Actavis Mid Atlantic Llc, Valeant International Barbados Srl, Zo Skin Health, Anchen Pharmaceuticals Inc, Mylan Pharmaceuticals Inc, Allergan Sales Llc, Cheplapharm Arzneimittel Gmbh, Almirall Llc, Wockhardt Eu Operations (Swiss) Ag, Solaris Pharma Corp

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Retinoic acid receptor PROTEIN FAMILY AGONIST CHEMBL2363069

Unichem Links

Atlas tretinoin all-trans retinoic acid 9-cis retinoic-acid retinoic acid
SureChEMBL SCHEMBL3145 SCHEMBL19091395
PharmGKB PA164746900
Human Metabolome Database HMDB0001852
DrugBank DB00755
PubChem: Thomson Pharma 14825303 14849563
PubChem 444795
NMRShiftDB 60021090
LINCS LSM-42854
Nikkaji J690.379G J1.313.469C J494.243D J970.183D J646.158A J528.606I J646.157C J1.518K J2.378.058E J623.910B
PDBe REA
BindingDB 323588 31883
EPA CompTox Dashboard DTXSID7021239
LipidMaps LMPR01090019
DrugCentral 2722
Metabolights MTBLC15367
Brenda 2354 12679 6481 193381 21231 5126
ChemicalBook CB6222631
Guide to Pharmacology 2644
rxnorm RENOVA TRETINOIN AVITA RETIN-A TRETINOIN MICROSPHERE ALTRENO ACTICIN ATRALIN
PubChem: Drugs of the Future 12014646
KEGG Ligand C00777
ChEBI 15367
ZINC ZINC000012358651