Tretinoin
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Scientific Name
Tretinoin
Description of the Drug
Tretinoin is a vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00755
http://www.drugbank.ca/drugs/DB00755
Brand Name(s)
Acticin, Altreno, Atralin, Avita, Renova, Retin-a, Retin-a micro, Retin-a-micro, Tretinoin, Tretin-X, Vesanoid
Company Owner(s)
Actavis Mid Atlantic Llc, Valeant International Barbados Srl, Zo Skin Health, Anchen Pharmaceuticals Inc, Mylan Pharmaceuticals Inc, Allergan Sales Llc, Cheplapharm Arzneimittel Gmbh, Almirall Llc, Wockhardt Eu Operations (Swiss) Ag, Solaris Pharma Corp
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Retinoic acid receptor | PROTEIN FAMILY | AGONIST | CHEMBL2363069 |
Clinical Trial(s)
Unichem Links
Atlas | tretinoin | all-trans retinoic acid | 9-cis retinoic-acid | retinoic acid | ||||||
SureChEMBL | SCHEMBL3145 | SCHEMBL19091395 | ||||||||
PharmGKB | PA164746900 | |||||||||
Human Metabolome Database | HMDB0001852 | |||||||||
DrugBank | DB00755 | |||||||||
PubChem: Thomson Pharma | 14825303 | 14849563 | ||||||||
PubChem | 444795 | |||||||||
NMRShiftDB | 60021090 | |||||||||
LINCS | LSM-42854 | |||||||||
Nikkaji | J690.379G | J1.313.469C | J494.243D | J970.183D | J646.158A | J528.606I | J646.157C | J1.518K | J2.378.058E | J623.910B |
PDBe | REA | |||||||||
BindingDB | 323588 | 31883 | ||||||||
EPA CompTox Dashboard | DTXSID7021239 | |||||||||
LipidMaps | LMPR01090019 | |||||||||
DrugCentral | 2722 | |||||||||
Metabolights | MTBLC15367 | |||||||||
Brenda | 2354 | 12679 | 6481 | 193381 | 21231 | 5126 | ||||
ChemicalBook | CB6222631 | |||||||||
Guide to Pharmacology | 2644 | |||||||||
rxnorm | RENOVA | TRETINOIN | AVITA | RETIN-A | TRETINOIN MICROSPHERE | ALTRENO | ACTICIN | ATRALIN | ||
PubChem: Drugs of the Future | 12014646 | |||||||||
KEGG Ligand | C00777 | |||||||||
ChEBI | 15367 | |||||||||
ZINC | ZINC000012358651 |