Tolcapone
Back to searchMolecule Structure
Scientific Name
Tolcapone
Description of the Drug
Tolcapone is a catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson’s disease.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00323
http://www.drugbank.ca/drugs/DB00323
Brand Name(s)
Tasmar, Tolcapone
Company Owner(s)
Alvogen Inc, Par Pharmaceutical Inc, Novast Laboratories Ltd, Mayne Pharma Llc, Bausch Health Us Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Catechol O-methyltransferase | SINGLE PROTEIN | INHIBITOR | CHEMBL2023 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL33869 | |
| PharmGKB | PA451720 | |
| Human Metabolome Database | HMDB0014468 | |
| DrugBank | DB00323 | |
| PubChem: Thomson Pharma | 15221967 | |
| PubChem | 4659569 | |
| NMRShiftDB | 10021705 | |
| LINCS | LSM-5282 | |
| PDBe | TCW | |
| BindingDB | 50108877 | |
| EPA CompTox Dashboard | DTXSID3023685 | |
| DrugCentral | 2697 | |
| Brenda | 23408 | |
| ChemicalBook | CB9302569 | |
| Guide to Pharmacology | 6646 | |
| rxnorm | TOLCAPONE | TASMAR |
| PubChem: Drugs of the Future | 12014507 | |
| KEGG Ligand | C07949 | |
| ChEBI | 63630 | |
| ZINC | ZINC000035342789 |
