Tolbutamide
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Scientific Name
Tolbutamide
Description of the Drug
Tolbutamide is a sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01124
http://www.drugbank.ca/drugs/DB01124
Brand Name(s)
Glyconon, Orinase, Pramidex, Rastinon, Tolbutamide
Company Owner(s)
Parke Davis Div Warner Lambert Co, Dava Pharmaceuticals Inc, Sandoz Inc, Ascot Hosp Pharmaceuticals Inc Div Travenol Laboratories Inc, Watson Laboratories Inc, Alra Laboratories Inc, Chartwell Rx Sciences Llc, Vangard Laboratories Inc Div Midway Medical Co, Ani Pharmaceuticals Inc, Mylan Pharmaceuticals Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Sulfonylurea receptor 1, Kir6.2 | PROTEIN COMPLEX | BLOCKER | CHEMBL2096972 |
Clinical Trial(s)
Unichem Links
| Atlas | tolbutamide | |
| SureChEMBL | SCHEMBL15918 | |
| PharmGKB | PA451718 | |
| Human Metabolome Database | HMDB0015256 | |
| DrugBank | DB01124 | |
| PubChem: Thomson Pharma | 15197366 | |
| PubChem | 5505 | |
| Mcule | MCULE-9720356859 | |
| NMRShiftDB | 60020895 | |
| LINCS | LSM-3907 | |
| Nikkaji | J1.406K | |
| BindingDB | 50027886 | |
| EPA CompTox Dashboard | DTXSID8021359 | |
| DrugCentral | 2696 | |
| Metabolights | MTBLC27999 | |
| Brenda | 9280 | |
| ChemicalBook | CB4709039 | |
| Guide to Pharmacology | 6848 | |
| rxnorm | TOLBUTAMIDE | TOLBUTAMIDE SODIUM |
| KEGG Ligand | C07148 | |
| ChEBI | 27999 | |
| ZINC | ZINC000001530703 |
