Tofacitinib

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Molecule Structure

Scientific Name

Tofacitinib

Description of the Drug

Tofacitinib is a Janus kinase (JAK) inhibitor used to treat rheumatic conditions, such as rheumatoid arthritis and ankylosing spondylitis, and ulcerative colitis.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB08895

Brand Name(s)

Not Available

Company Owner(s)

Zydus Pharmaceuticals Usa Inc, Pf Prism Cv, Ajanta Pharma Ltd, Pfizer Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Janus Kinase (JAK) PROTEIN FAMILY INHIBITOR CHEMBL2363062

Unichem Links

SureChEMBL SCHEMBL322753
DrugBank DB08895
PubChem: Thomson Pharma 14898931 16573063
PubChem 9926791
LINCS LSM-1227
Nikkaji J2.740.060D
PDBe MI1
BindingDB 50193995
EPA CompTox Dashboard DTXSID90197271
DrugCentral 4713
Brenda 155478 77457 27073 154591
Guide to Pharmacology 5677
rxnorm TOFACITINIB TOFACITINIB CITRATE XELJANZ
ChEBI 71200
ZINC ZINC000003818808