Scientific Name: Timolol
Brand Name: Azarga, Betimol, Combigan, Cosopt, Duotrav, Istalol, Timoptic, Xalacom
Company Owner: Santen oy, Falcon pharmaceuticals ltd, Aton pharma inc, Ista pharmaceuticals, Akorn inc, Bausch and lomb pharmaceuticals inc, Bausch and lomb inc, Falcon pharmaceuticals inc, Fdc ltd, E fougera div altana inc, Hi tech pharmacal co inc, Novex pharma, Pacific pharma inc, Pacific pharma, Wockhardt ltd, Merck research laboratories div merck co inc, Mylan pharmaceuticals inc, Quantum pharmics ltd, Sandoz inc, Teva pharmaceuticals usa inc, Usl pharma inc, Watson laboratories inc
Mechanism Of Action Timolol competes with adrenergic neurotransmitters for binding to beta(1) -adrenergic receptors in the heart and the beta(2) -receptors in the vascular and bronchial smooth muscle. This leads to diminished actions of catecholamines, which normally bind to adrenergic receptors and exert sympathetic effects leading to an increase in blood pressure and heart rate.
Description of the Drug: Timolol is a non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00373