Thioguanine
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Scientific Name
Thioguanine
Description of the Drug
Tioguanine is a purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00352
http://www.drugbank.ca/drugs/DB00352
Brand Name(s)
Lanvis, Tabloid, Thioguanine
Company Owner(s)
Woodward Specialty Llc
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
DNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311221 |
Inosine-5′-monophosphate dehydrogenase (IMPDH) | PROTEIN FAMILY | INHIBITOR | CHEMBL2111369 |
Clinical Trial(s)
Unichem Links
Atlas | tioguanine | |||||||
SureChEMBL | SCHEMBL3701 | |||||||
PharmGKB | PA451663 | |||||||
Human Metabolome Database | HMDB0014496 | |||||||
DrugBank | DB00352 | |||||||
PubChem: Thomson Pharma | 15171129 | 49749672 | 14772534 | 16902289 | ||||
PubChem | 2723601 | |||||||
Mcule | MCULE-5787306636 | |||||||
NMRShiftDB | 70071589 | |||||||
LINCS | LSM-6723 | |||||||
Nikkaji | J21.274A | |||||||
PDBe | DX4 | |||||||
BindingDB | 50200099 | |||||||
EPA CompTox Dashboard | DTXSID6023652 | |||||||
DrugCentral | 2632 | |||||||
Brenda | 1253 | 51290 | 45935 | 14340 | 229093 | 29358 | 229094 | 29360 |
Rhea | 9555 | |||||||
ChemicalBook | CB6361837 | |||||||
Guide to Pharmacology | 6845 | |||||||
rxnorm | TABLOID | THIOGUANINE ANHYDROUS | THIOGUANINE | |||||
KEGG Ligand | C07648 | |||||||
ChEBI | 9555 | |||||||
ZINC | ZINC000006382803 |