Temsirolimus

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Molecule Structure

Scientific Name

Temsirolimus

Description of the Drug

Temsirolimus is a antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB06287

Brand Name(s)

Torisel

Company Owner(s)

Accord Healthcare Inc, Pf Prism Cv, Gland Pharma Ltd

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
FK506-binding protein 1A SINGLE PROTEIN INHIBITOR CHEMBL1902

Unichem Links

SureChEMBL SCHEMBL16848392 SCHEMBL18792
Human Metabolome Database HMDB0015632
DrugBank DB06287
PubChem: Thomson Pharma 14816760 14914596
PubChem 6918289
PDBe A4I
BindingDB 50343413
EPA CompTox Dashboard DTXSID2040945
DrugCentral 4161
ChemicalBook CB3506811
Guide to Pharmacology 5892
rxnorm TEMSIROLIMUS TORISEL
PubChem: Drugs of the Future 12014940
KEGG Ligand C15182
ChEBI 79699