Tacrolimus
Back to searchMolecule Structure
Scientific Name
Tacrolimus
Description of the Drug
Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00864
http://www.drugbank.ca/drugs/DB00864
Brand Name(s)
Prograf, Protopic, Tacrolimus
Company Owner(s)
Leo Pharma As, Alkem Laboratories Ltd, Heritage Pharma Labs Inc Dba Avet Pharmaceuticals Labs Inc, Sandoz Inc, Hospira Inc, Veloxis Pharmaceuticals Inc, Fougera Pharmaceuticals Inc, Astellas Pharma Us Inc, Accord Healthcare Inc, Glenmark Pharmaceuticals Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| FK506-binding protein 1A | SINGLE PROTEIN | INHIBITOR | CHEMBL1902 |
Clinical Trial(s)
Unichem Links
| Atlas | tacrolimus | |||||
| SureChEMBL | SCHEMBL3088 | |||||
| PharmGKB | PA451578 | |||||
| DrugBank | DB00864 | |||||
| PubChem: Thomson Pharma | 14815954 | 14889261 | ||||
| PubChem | 445643 | |||||
| LINCS | LSM-43009 | |||||
| Nikkaji | J313.679E | |||||
| PDBe | FK5 | |||||
| BindingDB | 50030448 | |||||
| EPA CompTox Dashboard | DTXSID5046354 | |||||
| LipidMaps | LMPK04000003 | |||||
| Metabolights | MTBLC61049 | |||||
| Brenda | 5400 | 229454 | 229453 | 229456 | 5545 | 229455 |
| ChemicalBook | CB9772399 | |||||
| Guide to Pharmacology | 6784 | |||||
| rxnorm | TACROLIMUS MONOHYDRATE | TACROLIMUS | PROGRAF | ENVARSUS | PROTOPIC | ANHYDROUS TACROLIMUS |
| PubChem: Drugs of the Future | 12013904 | |||||
| KEGG Ligand | C01375 | |||||
| ChEBI | 61049 | |||||
| ZINC | ZINC000169289411 |
