Molecule Structure

Scientific Name

Sotorasib

Description of the Drug

Sotorasib is an experimental KRAS inhibitor being investigated for the treatment of KRAS G12C mutant non small cell lung cancer, colorectal cancer, and appendix cancer.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB15569

Brand Name(s)

Lumakras

Company Owner(s)

Amgen Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
GTPase KRas SINGLE PROTEIN INHIBITOR CHEMBL2189121

Unichem Links

SureChEMBL SCHEMBL20560375
Human Metabolome Database HMDB0304845
DrugBank DB15569
PubChem 137278711
BindingDB 50514402
Metabolights MTBLC178199
ChemicalBook CB24858719 CB65475731
Guide to Pharmacology 10678
ChEBI 178199