Sotalol
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Scientific Name
Sotalol
Description of the Drug
Sotalol is a methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00489
http://www.drugbank.ca/drugs/DB00489
Brand Name(s)
Not Available
Company Owner(s)
Apotex Inc, Teva Pharmaceuticals Usa Inc, Impax Pharmaceuticals, Azurity Pharmaceuticals Inc, Oxford Pharmaceuticals Llc, Sun Pharmaceutical Industries Inc, Covis Pharma Gmbh, Watson Laboratories Inc, Epic Pharma Inc, Upsher Smith Laboratories Llc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Beta-1 adrenergic receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL213 |
| HERG | SINGLE PROTEIN | BLOCKER | CHEMBL240 |
| Beta-2 adrenergic receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL210 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL16407 | ||||
| PharmGKB | PA451457 | ||||
| Human Metabolome Database | HMDB0014632 | ||||
| DrugBank | DB00489 | ||||
| PubChem: Thomson Pharma | 14775037 | ||||
| PubChem | 5253 | ||||
| LINCS | LSM-1465 | ||||
| Nikkaji | J10.583J | ||||
| BindingDB | 25762 | ||||
| EPA CompTox Dashboard | DTXSID0023589 | ||||
| DrugCentral | 2464 | ||||
| Brenda | 114658 | ||||
| ChemicalBook | CB6277510 | ||||
| Guide to Pharmacology | 7297 | ||||
| rxnorm | SOTALOL | SOTALOL HYDROCHLORIDE | SOTYLIZE | SORINE | BETAPACE |
| KEGG Ligand | C07309 | ||||
| ChEBI | 63622 |
