Sitagliptin

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Molecule Structure

Scientific Name

Sitagliptin

Description of the Drug

Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01261

Brand Name(s)

Januvia

Company Owner(s)

Merck Sharp And Dohme Llc A Sub Of Merck And Co Inc, Merck Sharp And Dohme Corp

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Dipeptidyl peptidase IV SINGLE PROTEIN INHIBITOR CHEMBL284

Unichem Links

SureChEMBL SCHEMBL17783
PharmGKB PA164748978
Human Metabolome Database HMDB0015390
DrugBank DB01261
PubChem: Thomson Pharma 14904024 16466401
PubChem 4369359
Mcule MCULE-2101761133
LINCS LSM-5363
Nikkaji J2.231.708C
PDBe 715
BindingDB 11162
EPA CompTox Dashboard DTXSID70197572
DrugCentral 2448
Brenda 27125 151478 14136 39010
ChemicalBook CB01449778
Guide to Pharmacology 6286
rxnorm SITAGLIPTIN PHOSPHATE JANUVIA SITAGLIPTIN
ChEBI 40237
ZINC ZINC000001489478