Simvastatin
Back to searchMolecule Structure
Scientific Name
Simvastatin
Description of the Drug
Simvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00641
http://www.drugbank.ca/drugs/DB00641
Brand Name(s)
Flolipid, Lacersa, Ranzolont, Simvador, Simvastatin, Zocor, Zocor heart-pro
Company Owner(s)
Alkem Laboratories Ltd, Watson Laboratories Inc, Dr Reddys Laboratories Sa, Abbvie Inc, Mylan Pharmaceuticals Inc, Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Zydus Pharmaceuticals Usa Inc, Micro Labs Ltd, Accord Healthcare Inc, Ani Pharmaceuticals Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| HMG-CoA reductase | SINGLE PROTEIN | INHIBITOR | CHEMBL402 |
Clinical Trial(s)
Unichem Links
| Atlas | simvastatin | ||||
| SureChEMBL | SCHEMBL2471 | ||||
| PharmGKB | PA451363 | ||||
| Human Metabolome Database | HMDB0005007 | ||||
| DrugBank | DB00641 | ||||
| PubChem: Thomson Pharma | 14929313 | 14831549 | |||
| PubChem | 54454 | ||||
| Mcule | MCULE-8390617062 | ||||
| NMRShiftDB | 20168321 | ||||
| LINCS | LSM-2492 | ||||
| Nikkaji | J152.218C | ||||
| BindingDB | 50139181 | ||||
| EPA CompTox Dashboard | DTXSID0023581 | ||||
| DrugCentral | 2445 | ||||
| Brenda | 230090 | 230091 | 217314 | 39735 | 2311 |
| Guide to Pharmacology | 2955 | ||||
| rxnorm | FLOLIPID | SIMVASTATIN | ZOCOR | ||
| PubChem: Drugs of the Future | 12013879 | ||||
| ChEBI | 9150 | ||||
| ZINC | ZINC000003780893 |
