Simeprevir

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Molecule Structure

Scientific Name

Simeprevir

Description of the Drug

Simeprevir is a direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB06290

Brand Name(s)

Olysio

Company Owner(s)

Janssen Products Lp

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Hepatitis C virus serine protease, NS3/NS4A PROTEIN COMPLEX INHIBITOR CHEMBL2095231

Unichem Links

SureChEMBL SCHEMBL826061
DrugBank DB06290
PubChem: Thomson Pharma 50128567
PubChem 24873435
Nikkaji J3.352.107C
PDBe 30B
BindingDB 50336504
DrugCentral 4812
Brenda 159985 26671 159983
ChemicalBook CB82510099
Guide to Pharmacology 7367
rxnorm OLYSIO SIMEPREVIR SODIUM SIMEPREVIR
PubChem: Drugs of the Future 87551010
ChEBI 134743
ZINC ZINC000085540268