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Molecule Structure

Scientific Name


Description of the Drug

Selpercatinib is a RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations.

Source: DrugBank Online – Retrieved 2023-03-10 from

Brand Name(s)


Company Owner(s)

Loxo Oncology Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET CHIMERIC PROTEIN INHIBITOR CHEMBL3430888
Coiled-coil domain-containing protein 6/Tyrosine-protein kinase receptor RET CHIMERIC PROTEIN INHIBITOR CHEMBL3430904
Tyrosine-protein kinase receptor RET SINGLE PROTEIN INHIBITOR CHEMBL2041

Unichem Links

SureChEMBL SCHEMBL20071478
Human Metabolome Database HMDB0304865
DrugBank DB15685
PubChem 134436906
BindingDB 296429
DrugCentral 5393
ChemicalBook CB34805442
Guide to Pharmacology 10318