Sapropterin
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Scientific Name
Sapropterin
Description of the Drug
Sapropterin is a cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU).
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00360
http://www.drugbank.ca/drugs/DB00360
Brand Name(s)
Not Available
Company Owner(s)
Biomarin Pharmaceutical Inc, Annora Pharma Private Ltd, Par Pharmaceutical Inc, Dr Reddys Laboratories Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Phenylalanine-4-hydroxylase | SINGLE PROTEIN | ACTIVATOR | CHEMBL3076 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL258544 | |||||||||||||||
| Human Metabolome Database | HMDB0000027 | |||||||||||||||
| DrugBank | DB00360 | |||||||||||||||
| PubChem: Thomson Pharma | 15196443 | 16725801 | 14847463 | 26738584 | ||||||||||||
| PubChem | 135398654 | |||||||||||||||
| NMRShiftDB | 70108693 | |||||||||||||||
| Nikkaji | J463.663E | |||||||||||||||
| PDBe | H4B | |||||||||||||||
| BindingDB | 50373697 | |||||||||||||||
| EPA CompTox Dashboard | DTXSID1041138 | |||||||||||||||
| DrugCentral | 2612 | |||||||||||||||
| Metabolights | MTBLC59560 | |||||||||||||||
| Brenda | 49513 | 7070 | 10690 | 36180 | 2684 | 38809 | 8426 | 49868 | 1371 | 153573 | 252 | 954 | 153356 | 32467 | 46087 | 16679 |
| Rhea | 59560 | |||||||||||||||
| ChemicalBook | CB5479898 | |||||||||||||||
| Guide to Pharmacology | 5276 | |||||||||||||||
| rxnorm | SAPROPTERIN | SAPROPTERIN DIHYDROCHLORIDE | KUVAN | |||||||||||||
| KEGG Ligand | C00272 | |||||||||||||||
| ChEBI | 59560 | |||||||||||||||
| ZINC | ZINC000013585233 |
