Sacubitril

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Molecule Structure

Scientific Name

Sacubitril

Description of the Drug

Sacubitril is a neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB09292

Brand Name(s)

Not Available

Company Owner(s)

Novartis Pharmaceuticals Corp

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Neprilysin SINGLE PROTEIN INHIBITOR CHEMBL1944

Unichem Links

SureChEMBL SCHEMBL2707112
DrugBank DB09292
PubChem: Thomson Pharma 26673060
PubChem 9811834
LINCS LSM-45643
Nikkaji J3.050.252C
EPA CompTox Dashboard DTXSID20164370
DrugCentral 5012
Brenda 239140 160189
ChemicalBook CB62627304
Guide to Pharmacology 7857
rxnorm SACUBITRIL
ChEBI 134714
ZINC ZINC000003792417