Rolapitant

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Molecule Structure

Scientific Name

Rolapitant

Description of the Drug

Rolapitant is a neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB09291

Brand Name(s)

Varuby

Company Owner(s)

Tersera Therapeutics Llc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Neurokinin 1 receptor SINGLE PROTEIN ANTAGONIST CHEMBL249

Unichem Links

SureChEMBL SCHEMBL354305
DrugBank DB09291
PubChem: Thomson Pharma 15319052
PubChem 10311306
EPA CompTox Dashboard DTXSID90203740
DrugCentral 5027
ChemicalBook CB12628366
Guide to Pharmacology 5749
rxnorm ROLAPITANT HYDROCHLORIDE ROLAPITANT VARUBI
ChEBI 90908
ZINC ZINC000003816514